Vectors for Human SP140

Gene Information

  • Offical Gene Symbol SP140
  • Species Human (Homo sapiens)
  • Offical Full Name SP140 nuclear body protein
  • Other Aliases LYSP100; LYSP100-A; LYSP100-B
  • Other Desigations nuclear body protein SP140; lymphoid-restricted homolog of Sp100; lymphoid-specific SP100 homolog; nuclear autoantigen Sp-140; speckled 140 kDa
  • Gene Type protein-coding
  • 개요
    This gene encodes a member of the SP100 family of proteins, which are share common domains including an N-terminal homogeneously staining region domain followed by a SP100/autoimmune regulator/NucP41/P75/deformed epidermal autoregulatory factor domain, a plant homeobox zinc finger, and a bromodomain. The encoded protein is interferon-inducible and is expressed at high levels in the nuclei of leukocytes. Variants of this gene have been associated with multiple sclerosis, Crohn\'s disease, and chronic lymphocytic leukemia. Alternative splicing results in multiple variants. [provided by RefSeq, Aug 2016]
  • NCBI Gene ID 11262
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human SP140(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SP140 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $159
Human SP140 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
Human SP140 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
Human SP140 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $159
Human SP140 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SP140 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $99
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Human SP140 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $259
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Human SP140 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $99
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Human SP140 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SP140 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $99
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Human SP140 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $99
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Human SP140 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $259
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