Vectors for Human SORD

Gene Information

  • Offical Gene Symbol SORD
  • Species Human (Homo sapiens)
  • Offical Full Name sorbitol dehydrogenase
  • Other Aliases HEL-S-95n; RDH; SDH; SORD1; SORDD; XDH
  • Other Desigations sorbitol dehydrogenase; (R,R)-butanediol dehydrogenase; L-iditol 2-dehydrogenase; epididymis secretory sperm binding protein Li 95n; polyol dehydrogenase; ribitol dehydrogenase; xylitol dehydrogenase
  • Gene Type protein-coding
  • 개요
    Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.[supplied by OMIM, Jul 2010]
  • NCBI Gene ID 6652
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human SORD(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SORD expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $159
Human SORD expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
Human SORD expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
Human SORD expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $159
Human SORD expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SORD shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $99
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Human SORD shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $259
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Human SORD shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $99
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Human SORD shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SORD CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $99
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Human SORD CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $99
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Human SORD CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $259
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