Human SORCS3 벡터 - 렌티바이러스, AAV, shRNA & CRISPR I 벡터빌더

Gene Information

Offical Gene Symbol SORCS3
Species Human (Homo sapiens)
Offical Full Name sortilin related VPS10 domain containing receptor 3
Other Aliases SORCS
Other Desigations VPS10 domain-containing receptor SorCS3; VPS10 domain receptor protein SORCS 3 (SORCS3)
Gene Type protein-coding
개요
This gene encodes a type-I receptor transmembrane protein that is a member of the vacuolar protein sorting 10 receptor family. Proteins of this family are defined by a vacuolar protein sorting 10 domain at the N-terminus. The N-terminal segment of this domain has a consensus motif for proprotein convertase processing, and the C-terminal segment of this domain is characterized by ten conserved cysteine residues. The vacuolar protein sorting 10 domain is followed by a leucine-rich segment, a transmembrane domain, and a short C-terminal cytoplasmic domain that interacts with adaptor molecules. The transcript is expressed at high levels in the brain, and candidate gene studies suggest that genetic variation in this gene is associated with Alzheimer\'s disease. Consistent with this observation, knockdown of the gene in cell culture results in an increase in amyloid precursor protein processing. [provided by RefSeq, Dec 2014]
NCBI Gene ID 22986
RefSeq Transcript
NM_014978.3
RefSeq Protein
NP_055793.1
External Links NCBI | OMIM | Ensembl | HGNC | UCSC Genome Browser View
View ORF sequence of this gene »

Vector Description	Vector Type	Price
Human SORCS3 expression regular plasmid vector	Mammalian Gene Expression Vector Guide	From $189
Human SORCS3 expression lentivirus vector	Mammalian Gene Expression Lentiviral Vector Guide	From $189
Human SORCS3 expression adenovirus vector	Mammalian Gene Expression Adenoviral Vector Guide	From $189
Human SORCS3 expression AAV vector	Mammalian Gene Expression AAV Vector Guide	From $189
Human SORCS3 expression PiggyBac vector	Mammalian Gene Expression PiggyBac Vector Guide	From $189

Vector Description	Vector Type	Price
Human SORCS3 shRNA lentivirus vector	Mammalian shRNA Knockdown Lentiviral Vector Guide	$149	View Vector
Human SORCS3 shRNA adenovirus vector	Mammalian shRNA Knockdown Adenoviral Vector Guide	$299	View Vector
Human SORCS3 shRNA AAV vector	Mammalian shRNA Knockdown AAV Vector Guide	$149	View Vector
Human SORCS3 shRNA PiggyBac vector	Mammalian shRNA Knockdown PiggyBac Vector Guide	$149	View Vector

Vector Description	Vector Type	Price
Human SORCS3 CRISPR regular plasmid vector	Mammalian CRISPR Vector (Single gRNA) Guide	$149	View Vector
Human SORCS3 CRISPR lentivirus vector	Mammalian CRISPR Lentiviral Vector (Single gRNA) Guide	$149	View Vector
Human SORCS3 CRISPR adenovirus vector	Mammalian CRISPR Adenoviral Vector (Single gRNA) Guide	$299	View Vector

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