Vectors for Human SNTA1

Gene Information

  • Offical Gene Symbol SNTA1
  • Species Human (Homo sapiens)
  • Offical Full Name syntrophin alpha 1
  • Other Aliases LQT12; SNT1; TACIP1; dJ1187J4.5
  • Other Desigations alpha-1-syntrophin; 59 kDa dystrophin-associated protein A1 acidic component 1; acidic alpha 1 syntrophin; dystrophin-associated protein A1, 59kDa, acidic component; pro-TGF-alpha cytoplasmic domain-interacting protein 1; syntrophin-1
  • Gene Type protein-coding
  • 개요
    Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue. [provided by RefSeq, Jan 2013]
  • NCBI Gene ID 6640
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human SNTA1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SNTA1 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $159
Human SNTA1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
Human SNTA1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
Human SNTA1 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $159
Human SNTA1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SNTA1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $99
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Human SNTA1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $259
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Human SNTA1 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $99
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Human SNTA1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SNTA1 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $99
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Human SNTA1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $99
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Human SNTA1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $259
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