Vectors for Human SMOX

Gene Information

  • Offical Gene Symbol SMOX
  • Species Human (Homo sapiens)
  • Offical Full Name spermine oxidase
  • Other Aliases C20orf16; PAO; PAO-1; PAO1; PAOH; PAOH1; SMO
  • Other Desigations spermine oxidase; flavin containing amine oxidase; flavin-containing spermine oxidase; polyamine oxidase 1; putative cyclin G1 interacting protein
  • Gene Type protein-coding
  • 개요
    Polyamines are ubiquitous polycationic alkylamines which include spermine, spermidine, putrescine, and agmatine. These molecules participate in a broad range of cellular functions which include cell cycle modulation, scavenging reactive oxygen species, and the control of gene expression. These molecules also play important roles in neurotransmission through their regulation of cell-surface receptor activity, involvement in intracellular signalling pathways, and their putative roles as neurotransmitters. This gene encodes an FAD-containing enzyme that catalyzes the oxidation of spermine to spermadine and secondarily produces hydrogen peroxide. Multiple transcript variants encoding different isoenzymes have been identified for this gene, some of which have failed to demonstrate significant oxidase activity on natural polyamine substrates. The characterized isoenzymes have distinctive biochemical characteristics and substrate specificities, suggesting the existence of additional levels of complexity in polyamine catabolism. [provided by RefSeq, Jul 2012]
  • NCBI Gene ID 54498
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human SMOX(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SMOX expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $159
Human SMOX expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
Human SMOX expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
Human SMOX expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $159
Human SMOX expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SMOX shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $99
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Human SMOX shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $259
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Human SMOX shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $99
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Human SMOX shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SMOX CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $99
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Human SMOX CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $99
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Human SMOX CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $259
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