Vectors for Human SLC6A5

Gene Information

  • Offical Gene Symbol SLC6A5
  • Species Human (Homo sapiens)
  • Offical Full Name solute carrier family 6 member 5
  • Other Aliases GLYT-2; GLYT2; HKPX3; NET1
  • Other Desigations sodium- and chloride-dependent glycine transporter 2; norepinephrine transporter 1; solute carrier family 6 (neurotransmitter transporter, glycine), member 5
  • Gene Type protein-coding
  • 개요
    This gene encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]
  • NCBI Gene ID 9152
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human SLC6A5(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SLC6A5 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human SLC6A5 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human SLC6A5 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human SLC6A5 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human SLC6A5 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SLC6A5 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human SLC6A5 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human SLC6A5 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human SLC6A5 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human SLC6A5 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human SLC6A5 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human SLC6A5 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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