Vectors for Human LOC108863620

Gene Information

  • Offical Gene Symbol LOC108863620
  • Species Human (Homo sapiens)
  • Offical Full Name -
  • Other Aliases -
  • Other Desigations -
  • Gene Type biological-region
  • 개요
    This record encompasses the promoter and nearby elements that regulate expression of the steroidogenic acute regulatory protein (STAR) gene. Activity of this region is stimulated by cyclic AMP, and regulated through signalling by various factors, including angiotensin II, prostaglandin E2, and aryl hydrocarbons. The proximal promoter sequence is conserved in mammals and includes recognition sites for nuclear receptor subfamily 5 group A member 1 (Nr5a1/Sf1), CCAAT/enhancer binding proteins, and sterol regulatory element binding transcription factor 1, which act as positive regulators of transcription. Nuclear receptor subfamily 0 group B member 1 (Nr0b1/Dax1) binds close to the putative TATA box and negatively regulates activity of this sequence. A distal regulatory region located approximately 3 kb from the transcription start site contains additional Nr5a1/Sf1 binding sites and was shown by chromatin conformation analysis to associate with the proximal promoter. [provided by RefSeq, Oct 2016]
  • NCBI Gene ID 108863620
  • External Links NCBI UCSC Genome Browser View
No vectors are found in our database for this gene. We may introduce vectors for this gene in the future.

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