Vectors for Human FMO1

Gene Information

  • Offical Gene Symbol FMO1
  • Species Human (Homo sapiens)
  • Offical Full Name flavin containing dimethylaniline monoxygenase 1
  • Other Aliases -
  • Other Desigations dimethylaniline monooxygenase [N-oxide-forming] 1; FMO 1; Flavin-containing monooxygenase 1 (fetal liver); dimethylaniline oxidase 1; fetal hepatic flavin-containing monooxygenase 1; flavin containing monooxygenase 1
  • Gene Type protein-coding
  • 개요
    Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
  • NCBI Gene ID 2326
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human FMO1(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human FMO1 expression 일반 plasmid vector Mammalian Gene Expression Vector   Guide  From $159
Human FMO1 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
Human FMO1 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
Human FMO1 expression 아데노부속바이러스 (AAV) vector Mammalian Gene Expression AAV Vector   Guide  From $159
Human FMO1 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human FMO1 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $99
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Human FMO1 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $259
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Human FMO1 shRNA 아데노부속바이러스 (AAV) vector Mammalian shRNA Knockdown AAV Vector   Guide  $99
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Human FMO1 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human FMO1 CRISPR 일반 plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $99
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Human FMO1 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $99
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Human FMO1 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $259
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