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Vectors for Human FGR

Gene Information

  • Offical Gene Symbol FGR
  • Species Human (Homo sapiens)
  • Offical Full Name FGR proto-oncogene, Src family tyrosine kinase
  • Other Aliases SRC2; c-fgr; c-src2; p55-Fgr; p55c-fgr; p58-Fgr; p58c-fgr
  • Other Desigations tyrosine-protein kinase Fgr; Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog; c-fgr protooncogene; c-src-2 proto-oncogene; feline Gardner-Rasheed sarcoma viral oncogene homolog; p55-c-fgr protein; proto-oncogene c-Fgr; proto-oncogene tyrosine-protein kinase FGR; v-fgr feline Gardner-Rasheed sarcoma viral oncogene homolog
  • Gene Type protein-coding
  • 개요
    This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 2268
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNC |  UCSC Genome Browser View
  • View ORF sequence of this gene »

Questions

Popular Vector Designs for Human FGR(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human FGR expression regular plasmid vector Mammalian Gene Expression Vector   Guide 
From $189
Human FGR expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide 
From $189
Human FGR expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide 
From $189
Human FGR expression AAV vector Mammalian Gene Expression AAV Vector   Guide 
From $189
Human FGR expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide 
From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human FGR shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide 
$149
View Vector 
Human FGR shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide 
$299
View Vector 
Human FGR shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide 
$149
View Vector 
Human FGR shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide 
$149
View Vector 
CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human FGR CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide 
$149
View Vector 
Human FGR CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide 
$149
View Vector 
Human FGR CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide 
$299
View Vector 

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