Vectors for Human FDPS

Gene Information

  • Offical Gene Symbol FDPS
  • Species Human (Homo sapiens)
  • Offical Full Name farnesyl diphosphate synthase
  • Other Aliases FPPS; FPS; POROK9
  • Other Desigations farnesyl pyrophosphate synthase; (2E,6E)-farnesyl diphosphate synthase; FPP synthase; FPP synthetase; farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase
  • Gene Type protein-coding
  • 개요
    This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008]
  • NCBI Gene ID 2224
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human FDPS(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human FDPS expression 일반 plasmid vector Mammalian Gene Expression Vector   Guide  From $159
Human FDPS expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $159
Human FDPS expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $159
Human FDPS expression 아데노부속바이러스 (AAV) vector Mammalian Gene Expression AAV Vector   Guide  From $159
Human FDPS expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $159
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human FDPS shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $99
View Vector 
Human FDPS shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $259
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Human FDPS shRNA 아데노부속바이러스 (AAV) vector Mammalian shRNA Knockdown AAV Vector   Guide  $99
View Vector 
Human FDPS shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $99
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human FDPS CRISPR 일반 plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $99
View Vector 
Human FDPS CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $99
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Human FDPS CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $259
View Vector 

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