Vectors for Human FBXW2

Gene Information

  • Offical Gene Symbol FBXW2
  • Species Human (Homo sapiens)
  • Offical Full Name F-box and WD repeat domain containing 2
  • Other Aliases FBW2; Fwd2; Md6
  • Other Desigations F-box/WD repeat-containing protein 2; F-box and WD-40 domain protein 2; F-box and WD-40 domain-containing protein 2
  • Gene Type protein-coding
  • 개요
    F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats. [provided by RefSeq, Jul 2008]
  • NCBI Gene ID 26190
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human FBXW2(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human FBXW2 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human FBXW2 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human FBXW2 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human FBXW2 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human FBXW2 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human FBXW2 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human FBXW2 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human FBXW2 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human FBXW2 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human FBXW2 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human FBXW2 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human FBXW2 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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