Vectors for Human FBXL18

Gene Information

  • Offical Gene Symbol FBXL18
  • Species Human (Homo sapiens)
  • Offical Full Name F-box and leucine rich repeat protein 18
  • Other Aliases Fbl18
  • Other Desigations F-box/LRR-repeat protein 18
  • Gene Type protein-coding
  • 개요
    The protein encoded by this gene is a member of a family of proteins that contain an approximately 40-amino acid F-box motif. This motif is important for interaction with SKP1 and for targeting some proteins for degradation. The encoded protein has been shown to control the cellular level of FBXL7, a protein that induces mitotic arrest, by targeting it for polyubiquitylation and proteasomal degradation. Members of the F-box protein family, such as FBXL18, are characterized by an approximately 40-amino acid F-box motif. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains. [provided by RefSeq, Mar 2016]
  • NCBI Gene ID 80028
  • RefSeq Transcript
  • RefSeq Protein
  • External Links NCBI  | OMIM  | Ensembl  | HGNCUCSC Genome Browser View

Popular Vector Designs for Human FBXL18(These vectors can be made very quickly)

Gene Expression Vectors
These designs are created with VectorBuilder’s standard backbones containing a ubiquitous promoter driving the ORF of your gene. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human FBXL18 expression regular plasmid vector Mammalian Gene Expression Vector   Guide  From $189
Human FBXL18 expression lentivirus vector Mammalian Gene Expression Lentiviral Vector   Guide  From $189
Human FBXL18 expression adenovirus vector Mammalian Gene Expression Adenoviral Vector   Guide  From $189
Human FBXL18 expression AAV vector Mammalian Gene Expression AAV Vector   Guide  From $189
Human FBXL18 expression PiggyBac vector Mammalian Gene Expression PiggyBac Vector   Guide  From $189
shRNA Knockdown Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving an shRNA targeting your gene of interest. A marker (e.g. EGFP) is placed in the vector where appropriate.
Vector Description Vector Type Marker Price
Human FBXL18 shRNA lentivirus vector Mammalian shRNA Knockdown Lentiviral Vector   Guide  $149
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Human FBXL18 shRNA adenovirus vector Mammalian shRNA Knockdown Adenoviral Vector   Guide  $299
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Human FBXL18 shRNA AAV vector Mammalian shRNA Knockdown AAV Vector   Guide  $149
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Human FBXL18 shRNA PiggyBac vector Mammalian shRNA Knockdown PiggyBac Vector   Guide  $149
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CRISPR Vectors
These designs are created with VectorBuilder’s standard backbones containing a U6 promoter driving a gRNA targeting your gene of interest. A marker (e.g. EGFP) is place in the vector where appropriate.
Vector Description Vector Type Marker Price
Human FBXL18 CRISPR regular plasmid vector Mammalian CRISPR Vector (Single gRNA)   Guide  $149
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Human FBXL18 CRISPR lentivirus vector Mammalian CRISPR Lentiviral Vector (Single gRNA)   Guide  $149
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Human FBXL18 CRISPR adenovirus vector Mammalian CRISPR Adenoviral Vector (Single gRNA)   Guide  $299
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